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Identification of nonessential regions of the nsp2 protein of an attenuated vaccine strain (HuN4-F112) of highly pathogenic porcine reproductive and respiratory syndrome virus for replication in marc-145 cell
BACKGROUND: The regions in the middle of nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome virus (PRRSV) have been shown to be nonessential for PRRSV replication, and these nonessential regions are different in various viral strains. FINDING: In this study, the nonessen...
Autores principales: | Xu, Yan-Zhao, Zhou, Yan-Jun, Zhang, Shan-Rui, Tong, Wu, Li, Ling, Jiang, Yi-Feng, Tong, Guang-Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422162/ https://www.ncbi.nlm.nih.gov/pubmed/22856599 http://dx.doi.org/10.1186/1743-422X-9-141 |
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