A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development

BACKGROUND: Epidemiological studies have suggested that the encounter with commensal microorganisms during the neonatal period is essential for normal development of the host immune system. Basic research involving gnotobiotic mice has demonstrated that colonization at the age of 5 weeks is too late...

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Detalles Bibliográficos
Autores principales: Yamamoto, Masahiro, Yamaguchi, Rui, Munakata, Kaori, Takashima, Kiyoe, Nishiyama, Mitsue, Hioki, Kyoji, Ohnishi, Yasuyuki, Nagasaki, Masao, Imoto, Seiya, Miyano, Satoru, Ishige, Atsushi, Watanabe, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422195/
https://www.ncbi.nlm.nih.gov/pubmed/22823934
http://dx.doi.org/10.1186/1471-2164-13-335

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