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Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation
BACKGROUND: The chemokine CCL2 has an important role in the recruitment of inflammatory cells into the central nervous system (CNS). A transgenic mouse model that overexpresses CCL2 in the CNS shows an accumulation of leukocytes within the perivascular space surrounding vessels, and which infiltrate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422203/ https://www.ncbi.nlm.nih.gov/pubmed/22546091 http://dx.doi.org/10.1186/2045-8118-9-10 |