Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

BACKGROUND: The chemokine CCL2 has an important role in the recruitment of inflammatory cells into the central nervous system (CNS). A transgenic mouse model that overexpresses CCL2 in the CNS shows an accumulation of leukocytes within the perivascular space surrounding vessels, and which infiltrate...

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Detalles Bibliográficos
Autores principales: Schellenberg, Angela E, Buist, Richard, Del Bigio, Marc R, Toft-Hansen, Henrik, Khorooshi, Reza, Owens, Trevor, Peeling, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422203/
https://www.ncbi.nlm.nih.gov/pubmed/22546091
http://dx.doi.org/10.1186/2045-8118-9-10

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