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The Multi-Targeted Kinase Inhibitor Sunitinib Induces Apoptosis in Colon Cancer Cells via PUMA

Constitutive activation of pro-survival kinases has become a promising target of small molecules with an increasing interest in developing multi-targeted agents. The mechanisms underlying the responsiveness to most agents targeting cancer specific survival pathways are still poorly understood but cr...

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Detalles Bibliográficos
Autores principales:	Sun, Jing, Sun, Quanhong, Brown, Matthew F., Dudgeon, Crissy, Chandler, Julie, Xu, Xiang, Shu, Yongqian, Zhang, Lin, Yu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422222/ https://www.ncbi.nlm.nih.gov/pubmed/22912816 http://dx.doi.org/10.1371/journal.pone.0043158

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