A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation

Chemokines play a key role in leukocyte recruitment during inflammation and are implicated in the pathogenesis of a number of autoimmune diseases. As such, inhibiting chemokine signaling has been of keen interest for the development of therapeutic agents. This endeavor, however, has been hampered du...

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Detalles Bibliográficos
Autores principales: Scalley-Kim, Michelle L., Hess, Bruce W., Kelly, Ryan L., Krostag, Anne-Rachel F., Lustig, Kurt H., Marken, John S., Ovendale, Pamela J., Posey, Aaron R., Smolak, Pamela J., Taylor, Janelle D. L., Wood, C. L., Bienvenue, David L., Probst, Peter, Salmon, Ruth A., Allison, Daniel S., Foy, Teresa M., Raport, Carol J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422223/
https://www.ncbi.nlm.nih.gov/pubmed/22912856
http://dx.doi.org/10.1371/journal.pone.0043332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422223/
https://www.ncbi.nlm.nih.gov/pubmed/22912856
http://dx.doi.org/10.1371/journal.pone.0043332

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