Cargando…

Phosphoproteome of Human Glioblastoma Initiating Cells Reveals Novel Signaling Regulators Encoded by the Transcriptome

BACKGROUND: Glioblastoma is one of the most aggressive tumors with poor prognosis. Although various studies have been performed so far, there are not effective treatments for patients with glioblastoma. METHODOLOGY/PRINCIPAL FINDINGS: In order to systematically elucidate the aberrant signaling machi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kozuka-Hata, Hiroko, Nasu-Nishimura, Yukiko, Koyama-Nasu, Ryo, Ao-Kondo, Hiroko, Tsumoto, Kouhei, Akiyama, Tetsu, Oyama, Masaaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422224/ https://www.ncbi.nlm.nih.gov/pubmed/22912867 http://dx.doi.org/10.1371/journal.pone.0043398

Ejemplares similares

The Cancer Stem Cell Marker CD133 Interacts with Plakoglobin and Controls Desmoglein-2 Protein Levels
por: Koyama-Nasu, Ryo, et al.
Publicado: (2013)

Phosphoproteomics-Based Systems Analysis of Signal Transduction Networks
por: Kozuka-Hata, Hiroko, et al.
Publicado: (2012)

System-Wide Analysis of Protein Acetylation and Ubiquitination Reveals a Diversified Regulation in Human Cancer Cells
por: Kozuka-Hata, Hiroko, et al.
Publicado: (2020)

Real-Time Search-Assisted Multiplexed Quantitative Proteomics Reveals System-Wide Translational Regulation of Non-Canonical Short Open Reading Frames
por: Kozuka-Hata, Hiroko, et al.
Publicado: (2023)

Phosphoproteomics-Based Modeling Defines the Regulatory Mechanism Underlying Aberrant EGFR Signaling
por: Tasaki, Shinya, et al.
Publicado: (2010)

The CCR4–NOT complex suppresses untimely translational activation of maternal mRNAs
por: Soeda, Shou, et al.
Publicado: (2023)

A High-Resolution Map of SBP1 Interactomes in Plasmodium falciparum-infected Erythrocytes
por: Takano, Ryo, et al.
Publicado: (2019)

Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals
por: Narita, Keishi, et al.
Publicado: (2012)

Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway
por: Yamaguchi, Noritaka, et al.
Publicado: (2013)

The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice
por: Nakamura, Tsutomu, et al.
Publicado: (2018)

Discovery of a Vertebrate-Specific Factor that Processes Flagellar Glycolytic Enolase during Motile Ciliogenesis
por: Narita, Keishi, et al.
Publicado: (2020)

Shotgun proteomics deciphered age/division of labor-related functional specification of three honeybee (Apis mellifera L.) exocrine glands
por: Fujita, Toshiyuki, et al.
Publicado: (2018)

Tks5-dependent formation of circumferential podosomes mediates cell-cell fusion
por: Oikawa, Tsukasa, et al.
Publicado: (2012)

Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion
por: Oikawa, Tsukasa, et al.
Publicado: (2012)

USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock
por: Hirano, Arisa, et al.
Publicado: (2016)

Ubiquitin-specific protease 9X in host cells interacts with herpes simplex virus 1 ICP0
por: SATO, Yuka, et al.
Publicado: (2015)

Osmostress enhances activating phosphorylation of Hog1 MAP kinase by mono‐phosphorylated Pbs2 MAP2K
por: Tatebayashi, Kazuo, et al.
Publicado: (2020)

AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction
por: Saito, Ayumu, et al.
Publicado: (2007)

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole
por: Ohta, Midori, et al.
Publicado: (2014)

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
por: Fukui, Ryutaro, et al.
Publicado: (2009)

Effects of a remote mutation from the contact paratope on the structure of CDR-H3 in the anti-HIV neutralizing antibody PG16
por: Kondo, Hiroko X., et al.
Publicado: (2019)

ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II
por: Ohe, Seina, et al.
Publicado: (2022)

A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation
por: Tsuboyama, Kotaro, et al.
Publicado: (2020)

Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
por: Yamaguchi, Kiyoshi, et al.
Publicado: (2023)

Determination of a phosphorylation site in Nipah virus nucleoprotein and its involvement in virus transcription
por: Huang, Mingshu, et al.
Publicado: (2011)

miRNAs in Normal and Malignant Hematopoiesis
por: Kotaki, Ryutaro, et al.
Publicado: (2017)

PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABA(A) receptor trafficking
por: Nakamura, Tsutomu, et al.
Publicado: (2016)

Addition of arginine hydrochloride and proline to the culture medium enhances recombinant protein expression in Brevibacillus choshinensis: The case of RBD of SARS-CoV-2 spike protein and its antibody
por: Matsunaga, Ryo, et al.
Publicado: (2022)

Enhanced access to the human phosphoproteome with genetically encoded phosphothreonine
por: Moen, Jack M., et al.
Publicado: (2022)

CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy
por: Hara, Ayaka, et al.
Publicado: (2020)

Generation of biparatopic antibody through two-step targeting of fragment antibodies on antigen using SpyTag and SpyCatcher
por: Akiba, Hiroki, et al.
Publicado: (2020)

Prolonged severe neutropenia after the first daratumumab administration for multiple myeloma with baseline neutropenia
por: Nakamura, Fumihiko, et al.
Publicado: (2019)

Identification of key modules and hub genes for small-cell lung carcinoma and large-cell neuroendocrine lung carcinoma by weighted gene co-expression network analysis of clinical tissue-proteomes
por: Nakamura, Haruhiko, et al.
Publicado: (2019)

Mouse gingival single-cell transcriptomic atlas: An activated fibroblast subpopulation guides oral barrier immunity in periodontitis
por: Kondo, Takeru, et al.
Publicado: (2023)

ASBEL, an ANA/BTG3 antisense transcript required for tumorigenicity of ovarian carcinoma
por: Yanagida, Satoshi, et al.
Publicado: (2013)

Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody
por: Akiba, Hiroki, et al.
Publicado: (2019)

Mouse gingival single-cell transcriptomic atlas identified a novel fibroblast subpopulation activated to guide oral barrier immunity in periodontitis
por: Kondo, Takeru, et al.
Publicado: (2023)

Cell cycle-dependent gene networks for cell proliferation activated by nuclear CK2α complexes
por: Homma, Miwako Kato, et al.
Publicado: (2023)

Stress-dependent cell stiffening by tardigrade tolerance proteins that reversibly form a filamentous network and gel
por: Tanaka, Akihiro, et al.
Publicado: (2022)

Detection of the Heterogeneous O-Glycosylation Profile of MT1-MMP Expressed in Cancer Cells by a Simple MALDI-MS Method
por: Shuo, Takuya, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_hahejh4q8dlsnc2979nn6rnn0o