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Simultaneous Detection of Ca(2+) and Diacylglycerol Signaling in Living Cells
Phospholipase C produces two second messengers - diacylglycerol (DAG), which remains in the membrane, and inositol triphosphate (IP(3)), which triggers the release of calcium ions (Ca(2+)) from intracellular stores. Genetically encoded sensors based on a single circularly permuted fluorescent protei...
Autores principales: | Tewson, Paul, Westenberg, Mara, Zhao, Yongxin, Campbell, Robert E., Quinn, Anne Marie, Hughes, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422227/ https://www.ncbi.nlm.nih.gov/pubmed/22912738 http://dx.doi.org/10.1371/journal.pone.0042791 |
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