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Prediction of the Pharmacokinetic Parameters of Triptolide in Rats Based on Endogenous Molecules in Pre-Dose Baseline Serum

BACKGROUND: Individual variances usually affect drug metabolism and disposition, and hence result in either ineffectiveness or toxicity of a drug. In addition to genetic polymorphism, the multiple confounding factors of lifestyles, such as dietary preferences, contribute partially to individual vari...

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Detalles Bibliográficos
Autores principales:	Liu, Linsheng, Cao, Bei, Aa, Jiye, Zheng, Tian, Shi, Jian, Li, Mengjie, Wang, Xinwen, Zhao, Chunyan, Xiao, Wenjing, Yu, Xiaoyi, Sun, Runbin, Gu, Rongrong, Zhou, Jun, Wu, Liang, Hao, Gang, Zhu, Xuanxuan, Wang, Guangji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422234/ https://www.ncbi.nlm.nih.gov/pubmed/22912866 http://dx.doi.org/10.1371/journal.pone.0043389

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