Functional Selection of shRNA Loops from Randomized Retroviral Libraries

Gene silencing by RNA interference (RNAi) can be achieved by the ectopic expression of tailored short hairpin RNAs (shRNAs) which after export to the cytoplasm are processed by Dicer and incorporated into the RNA induced silencing complex (RISC). Design rules for shRNAs have been the focus of severa...

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Detalles Bibliográficos
Autores principales: Jensen, Stig Mølgaard Rask, Schmitz, Alexander, Pedersen, Finn Skou, Kjems, Jørgen, Bramsen, Jesper Bertram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422301/
https://www.ncbi.nlm.nih.gov/pubmed/22912797
http://dx.doi.org/10.1371/journal.pone.0043095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422301/
https://www.ncbi.nlm.nih.gov/pubmed/22912797
http://dx.doi.org/10.1371/journal.pone.0043095

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