Cargando…

Inhibition of PDGF-B Induction and Cell Growth by Syndecan-1 Involves the Ubiquitin and SUMO-1 Ligase, Topors

Syndecans are receptors for soluble ligands, including heparin-binding growth factors, and matrix proteins. However, intracellular targets of syndecan-1 (Sdc-1)-mediated signaling are not fully understood. A yeast two-hybrid protein interaction screening of a mouse embryo library identified the ubiq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braun, Kathleen R., DeWispelaere, Allison M., Bressler, Steven L., Fukai, Nozomi, Kenagy, Richard D., Chen, Lihua, Clowes, Alexander W., Kinsella, Michael G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422340/ https://www.ncbi.nlm.nih.gov/pubmed/22912899 http://dx.doi.org/10.1371/journal.pone.0043701

Ejemplares similares

Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice
por: Marshall, Henderson, et al.
Publicado: (2010)

TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene
por: Czub, Barbara, et al.
Publicado: (2016)

A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1
por: Westerbeck, Jason W., et al.
Publicado: (2014)

Genome maintenance in Saccharomyces cerevisiae: the role of SUMO and SUMO-targeted ubiquitin ligases
por: Jalal, Deena, et al.
Publicado: (2017)

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain
por: Sriramachandran, Annie M., et al.
Publicado: (2019)

SUMO-Targeted Ubiquitin Ligase, Rad60, and Nse2 SUMO Ligase Suppress Spontaneous Top1–Mediated DNA Damage and Genome Instability
por: Heideker, Johanna, et al.
Publicado: (2011)

SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability
por: Chang, Ya-Chu, et al.
Publicado: (2021)

Necdin Promotes Ubiquitin-Dependent Degradation of PIAS1 SUMO E3 Ligase
por: Gur, Ibrahim, et al.
Publicado: (2014)

The Biology of SUMO-Targeted Ubiquitin Ligases in Drosophila Development, Immunity, and Cancer
por: Abed, Mona, et al.
Publicado: (2018)

Preserving genome integrity: The vital role of SUMO-targeted ubiquitin ligases
por: Han, Jinhua, et al.
Publicado: (2023)

Mutations in the TOPORS gene cause 1% of autosomal dominant retinitis pigmentosa
por: Bowne, Sara J., et al.
Publicado: (2008)

Helicase/SUMO-targeted ubiquitin ligase Uls1 interacts with the Holliday junction resolvase Yen1
por: Bauer, Stefanie L., et al.
Publicado: (2019)

A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence
por: Boutell, Chris, et al.
Publicado: (2011)

Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination
por: Qiao, Huanyu, et al.
Publicado: (2014)

Physical and Genetic Associations of the Irc20 Ubiquitin Ligase with Cdc48 and SUMO
por: Richardson, Aaron, et al.
Publicado: (2013)

Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4
por: Xu, Yingqi, et al.
Publicado: (2014)

The SUMO-targeted ubiquitin ligase RNF4 regulates localization and function of the HTLV-1 oncoprotein Tax
por: Fryrear, Kimberly A, et al.
Publicado: (2011)

A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA
por: Parker, Joanne L., et al.
Publicado: (2012)

Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity
por: Liang, Jason, et al.
Publicado: (2017)

Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4
por: Lear, Travis, et al.
Publicado: (2016)

Concerted Action of the Ubiquitin-Fusion Degradation Protein 1 (Ufd1) and Sumo-Targeted Ubiquitin Ligases (STUbLs) in the DNA-Damage Response
por: Køhler, Julie Bonne, et al.
Publicado: (2013)

Physical and Genetic Interactions Between Uls1 and the Slx5–Slx8 SUMO-Targeted Ubiquitin Ligase
por: Tan, Wei, et al.
Publicado: (2013)

Centromere Binding and a Conserved Role in Chromosome Stability for SUMO-Dependent Ubiquitin Ligases
por: van de Pasch, Loes A. L., et al.
Publicado: (2013)

Correction: Physical and Genetic Associations of the Irc20 Ubiquitin Ligase with Cdc48 and SUMO
por: Richardson, Aaron, et al.
Publicado: (2013)

Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity
por: Chen, Lihua, et al.
Publicado: (2016)

Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2
por: Gareau, Jaclyn R., et al.
Publicado: (2012)

Structural Diversity of Ubiquitin E3 Ligase
por: Toma-Fukai, Sachiko, et al.
Publicado: (2021)

HTLV-1 Tax binds to and stabilizes the SUMO-targeted ubiquitin ligase RNF4 during DNA damage response
por: Guo, Xin, et al.
Publicado: (2014)

The yeast homologue of the microtubule-associated protein Lis1 interacts with the sumoylation machinery and a SUMO-targeted ubiquitin ligase
por: Alonso, Annabel, et al.
Publicado: (2012)

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response
por: Poulsen, Sara L., et al.
Publicado: (2013)

TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair
por: Hariharasudhan, Gurusamy, et al.
Publicado: (2022)

Expanding SUMO and ubiquitin-mediated signaling through hybrid SUMO-ubiquitin chains and their receptors
por: Guzzo, Catherine M., et al.
Publicado: (2013)

Real Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand Breaks
por: Dantuma, Nico P., et al.
Publicado: (2016)

PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
por: Belaguli, Narasimhaswamy S., et al.
Publicado: (2012)

EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells
por: Lu, Fang, et al.
Publicado: (2014)

Correction: PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
por: Belaguli, Narasimhaswamy S., et al.
Publicado: (2012)

Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4
por: Pfeiffer, Annika, et al.
Publicado: (2017)

Exonuclease containment by SUMO plus ubiquitin
por: Naegeli, Hanspeter
Publicado: (2015)

SUMO-targeted ubiquitin ligase activity can either suppress or promote genome instability, depending on the nature of the DNA lesion
por: Nie, Minghua, et al.
Publicado: (2017)

Cancer-Associated Dysregulation of Sumo Regulators: Proteases and Ligases
por: Lara-Ureña, Nieves, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eh8oqlb51n2udfk6udkl1d6g85