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Cell Surface Cdc37 Participates in Extracellular HSP90 Mediated Cancer Cell Invasion
Cdc37 is a 50 kDa molecular chaperone which targets intrinsically unstable protein kinases to the molecular chaperone HSP90. It is also an over-expressed oncoprotein that mediates carcinogenesis and maintenance of the malignant phenotype by stabilizing the compromised structures of mutant and/or ove...
Autores principales: | El Hamidieh, Avraam, Grammatikakis, Nicholas, Patsavoudi, Evangelia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422348/ https://www.ncbi.nlm.nih.gov/pubmed/22912728 http://dx.doi.org/10.1371/journal.pone.0042722 |
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