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Imaging Characteristics, Tissue Distribution, and Spread of a Novel Oncolytic Vaccinia Virus Carrying the Human Sodium Iodide Symporter
INTRODUCTION: Oncolytic viruses show promise for treating cancer. However, to assess therapy and potential toxicity, a noninvasive imaging modality is needed. This study aims to determine the in vivo biodistribution, and imaging and timing characteristics of a vaccinia virus, GLV-1h153, encoding the...
Autores principales: | Haddad, Dana, Chen, Chun-Hao, Carlin, Sean, Silberhumer, Gerd, Chen, Nanhai G., Zhang, Qian, Longo, Valerie, Carpenter, Susanne G., Mittra, Arjun, Carson, Joshua, Au, Joyce, Gonen, Mithat, Zanzonico, Pat B., Szalay, Aladar A., Fong, Yuman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422353/ https://www.ncbi.nlm.nih.gov/pubmed/22912675 http://dx.doi.org/10.1371/journal.pone.0041647 |
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