Novel Rare Variants in Congenital Cardiac Arrhythmia Genes are Frequent in Drug-induced Torsades de Pointes

Marked prolongation of the QT interval and polymorphic ventricular tachycardia following medication (drug-induced long QT syndrome, diLQTS) is a severe adverse drug reaction (ADR) that phenocopies congenital long QT syndrome (cLQTS) and one of the leading causes for drug withdrawal and relabeling. W...

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Detalles Bibliográficos
Autores principales: Ramirez, Andrea H., Shaffer, Christian M., Delaney, Jessica T., Sexton, David P., Levy, Shawn E., Rieder, Mark J., Nickerson, Deborah A., George, Alfred L., Roden, Dan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422407/
https://www.ncbi.nlm.nih.gov/pubmed/22584458
http://dx.doi.org/10.1038/tpj.2012.14

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