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Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report

INTRODUCTION: We report an instructive case of incidental renal cell carcinoma in a patient with autosomal dominant polycystic kidney disease who underwent simultaneous bilateral native nephrectomy and living donor renal transplantation. CASE PRESENTATION: A 57-year-old Asian man with end-stage kidn...

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Autores principales: Misumi, Toshihiro, Ide, Kentaro, Onoe, Takashi, Banshodani, Masataka, Tazawa, Hirofumi, Teraoka, Yoshifumi, Hotta, Ryuichi, Yamashita, Masahiro, Tashiro, Hirotaka, Ohdan, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423017/
https://www.ncbi.nlm.nih.gov/pubmed/22691223
http://dx.doi.org/10.1186/1752-1947-6-154
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author Misumi, Toshihiro
Ide, Kentaro
Onoe, Takashi
Banshodani, Masataka
Tazawa, Hirofumi
Teraoka, Yoshifumi
Hotta, Ryuichi
Yamashita, Masahiro
Tashiro, Hirotaka
Ohdan, Hideki
author_facet Misumi, Toshihiro
Ide, Kentaro
Onoe, Takashi
Banshodani, Masataka
Tazawa, Hirofumi
Teraoka, Yoshifumi
Hotta, Ryuichi
Yamashita, Masahiro
Tashiro, Hirotaka
Ohdan, Hideki
author_sort Misumi, Toshihiro
collection PubMed
description INTRODUCTION: We report an instructive case of incidental renal cell carcinoma in a patient with autosomal dominant polycystic kidney disease who underwent simultaneous bilateral native nephrectomy and living donor renal transplantation. CASE PRESENTATION: A 57-year-old Asian man with end-stage kidney disease due to autosomal dominant polycystic kidney disease received a living kidney graft from his brother. Because of recurrent infection, chronic pain and enlarged kidneys, he underwent a bilateral nephrectomy with concomitant renal transplantation. The total weight of the removed kidneys was 6kg; the maximal diameter of the larger kidney was 28cm. His left kidney had a 1cm diameter tumor. Pathology indicated papillary renal cell carcinoma. At the time of this report, the transplant kidney function was normal with no evidence of local recurrence or distant metastasis. CONCLUSION: This case shows and reinforces the importance of considering the possibility of an occult malignancy in the native kidneys of patients with autosomal dominant polycystic kidney disease. Simultaneous bilateral native nephrectomy should be considered in these renal transplant recipients not only for preventing the development of adverse symptoms but also for detecting an occult malignancy.
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spelling pubmed-34230172012-08-21 Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report Misumi, Toshihiro Ide, Kentaro Onoe, Takashi Banshodani, Masataka Tazawa, Hirofumi Teraoka, Yoshifumi Hotta, Ryuichi Yamashita, Masahiro Tashiro, Hirotaka Ohdan, Hideki J Med Case Rep Case Report INTRODUCTION: We report an instructive case of incidental renal cell carcinoma in a patient with autosomal dominant polycystic kidney disease who underwent simultaneous bilateral native nephrectomy and living donor renal transplantation. CASE PRESENTATION: A 57-year-old Asian man with end-stage kidney disease due to autosomal dominant polycystic kidney disease received a living kidney graft from his brother. Because of recurrent infection, chronic pain and enlarged kidneys, he underwent a bilateral nephrectomy with concomitant renal transplantation. The total weight of the removed kidneys was 6kg; the maximal diameter of the larger kidney was 28cm. His left kidney had a 1cm diameter tumor. Pathology indicated papillary renal cell carcinoma. At the time of this report, the transplant kidney function was normal with no evidence of local recurrence or distant metastasis. CONCLUSION: This case shows and reinforces the importance of considering the possibility of an occult malignancy in the native kidneys of patients with autosomal dominant polycystic kidney disease. Simultaneous bilateral native nephrectomy should be considered in these renal transplant recipients not only for preventing the development of adverse symptoms but also for detecting an occult malignancy. BioMed Central 2012-06-13 /pmc/articles/PMC3423017/ /pubmed/22691223 http://dx.doi.org/10.1186/1752-1947-6-154 Text en Copyright ©2012 Misumi et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Misumi, Toshihiro
Ide, Kentaro
Onoe, Takashi
Banshodani, Masataka
Tazawa, Hirofumi
Teraoka, Yoshifumi
Hotta, Ryuichi
Yamashita, Masahiro
Tashiro, Hirotaka
Ohdan, Hideki
Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
title Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
title_full Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
title_fullStr Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
title_full_unstemmed Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
title_short Incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
title_sort incidental renal cell carcinoma presenting in a renal transplant recipient with autosomal dominant polycystic kidney disease: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423017/
https://www.ncbi.nlm.nih.gov/pubmed/22691223
http://dx.doi.org/10.1186/1752-1947-6-154
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