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Combined Species Identification, Genotyping, and Drug Resistance Detection of Mycobacterium tuberculosis Cultures by MLPA on a Bead-Based Array
The population structure of Mycobacterium tuberculosis is typically clonal therefore genotypic lineages can be unequivocally identified by characteristic markers such as mutations or genomic deletions. In addition, drug resistance is mainly mediated by mutations. These issues make multiplexed detect...
Autores principales: | Bergval, Indra, Sengstake, Sarah, Brankova, Nadia, Levterova, Viktoria, Abadía, Edgar, Tadumaze, Nino, Bablishvili, Nino, Akhalaia, Maka, Tuin, Kiki, Schuitema, Anja, Panaiotov, Stefan, Bachiyska, Elizabeta, Kantardjiev, Todor, de Zwaan, Rina, Schürch, Anita, van Soolingen, Dick, van ‘t Hoog, Anja, Cobelens, Frank, Aspindzelashvili, Rusudan, Sola, Christophe, Klatser, Paul, Anthony, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423362/ https://www.ncbi.nlm.nih.gov/pubmed/22916230 http://dx.doi.org/10.1371/journal.pone.0043240 |
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