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Hoxa11 and Hoxd11 Regulate Chondrocyte Differentiation Upstream of Runx2 and Shox2 in Mice

During limb development, posterior Hox genes of the Hoxa- and Hoxd cluster provide positional information along the limb axis. Here we report a new function for Hoxa11 and Hoxd11 in regulating the early steps of chondrocyte differentiation. We analyzed forelimbs of Hoxa11(−/−);d11(−/−) and Ulnaless...

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Detalles Bibliográficos
Autores principales:	Gross, Stefanie, Krause, Yvonne, Wuelling, Manuela, Vortkamp, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423364/ https://www.ncbi.nlm.nih.gov/pubmed/22916278 http://dx.doi.org/10.1371/journal.pone.0043553

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