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Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis

BACKGROUND: Bacterial translocation is a frequent event in cirrhosis leading to an increased inflammatory response. Splanchnic adrenergic system hyperactivation has been related with increased bacterial translocation. We aim at evaluating the interacting mechanism between hepatic norepinephrine and...

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Detalles Bibliográficos
Autores principales: Zapater, Pedro, Gómez-Hurtado, Isabel, Peiró, Gloria, González-Navajas, José Manuel, García, Irma, Giménez, Paula, Moratalla, Alba, Such, José, Francés, Rubén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423372/
https://www.ncbi.nlm.nih.gov/pubmed/22916250
http://dx.doi.org/10.1371/journal.pone.0043371

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