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Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis
BACKGROUND: Bacterial translocation is a frequent event in cirrhosis leading to an increased inflammatory response. Splanchnic adrenergic system hyperactivation has been related with increased bacterial translocation. We aim at evaluating the interacting mechanism between hepatic norepinephrine and...
Autores principales: | Zapater, Pedro, Gómez-Hurtado, Isabel, Peiró, Gloria, González-Navajas, José Manuel, García, Irma, Giménez, Paula, Moratalla, Alba, Such, José, Francés, Rubén |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423372/ https://www.ncbi.nlm.nih.gov/pubmed/22916250 http://dx.doi.org/10.1371/journal.pone.0043371 |
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