Cell Cycle Regulation by the PRMT6 Arginine Methyltransferase through Repression of Cyclin-Dependent Kinase Inhibitors

PRMT6 belongs to the family of Protein Arginine Methyltransferase (PRMT) enzymes that catalyze the methylation of guanidino nitrogens of arginine residues. PRMT6 has been shown to modify the tail of histone H3, but the in vivo function of PRMT6 is largely unknown. Here, we show that PRMT6 regulates...

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Detalles Bibliográficos
Autores principales: Kleinschmidt, Markus A., de Graaf, Petra, van Teeffelen, Hetty A. A. M., Timmers, H. Th. Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423397/
https://www.ncbi.nlm.nih.gov/pubmed/22916108
http://dx.doi.org/10.1371/journal.pone.0041446

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