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Kinetics of Bulge Bases in Small RNAs and the Effect of Pressure on It
Due to their self-catalytic properties, small RNAs with bulge bases are hypothesized to be primordial molecules which could form elementary translation systems. Using molecular dynamics simulations, we study the binding propensity of small RNAs by calculating the free energy barrier corresponding to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423399/ https://www.ncbi.nlm.nih.gov/pubmed/22916118 http://dx.doi.org/10.1371/journal.pone.0042052 |