Human Neural Stem Cell Replacement Therapy for Amyotrophic Lateral Sclerosis by Spinal Transplantation

BACKGROUND: Mutation in the ubiquitously expressed cytoplasmic superoxide dismutase (SOD1) causes an inherited form of Amyotrophic Lateral Sclerosis (ALS). Mutant synthesis in motor neurons drives disease onset and early disease progression. Previous experimental studies have shown that spinal graft...

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Detalles Bibliográficos
Autores principales: Hefferan, Michael P., Galik, Jan, Kakinohana, Osamu, Sekerkova, Gabriela, Santucci, Camila, Marsala, Silvia, Navarro, Roman, Hruska-Plochan, Marian, Johe, Karl, Feldman, Eva, Cleveland, Don W., Marsala, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423406/
https://www.ncbi.nlm.nih.gov/pubmed/22916141
http://dx.doi.org/10.1371/journal.pone.0042614

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