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Sex-Specific Regulation of Mitochondrial DNA Levels: Genome-Wide Linkage Analysis to Identify Quantitative Trait Loci

Altered mitochondrial DNA (mtDNA) levels have been associated with common diseases in humans. We investigated the genetic mechanism that controls mtDNA levels using genome-wide linkage analyses in families from the Genetic Analysis of Idiopathic Thrombophilia Project (GAIT). We measure mtDNA levels...

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Detalles Bibliográficos
Autores principales: López, Sonia, Buil, Alfonso, Souto, Juan Carlos, Casademont, Jordi, Blangero, John, Martinez-Perez, Angel, Fontcuberta, Jordi, Lathrop, Mark, Almasy, Laura, Soria, Jose Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423410/
https://www.ncbi.nlm.nih.gov/pubmed/22916149
http://dx.doi.org/10.1371/journal.pone.0042711