Design and Synthesis of Potent N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitor as Anti-Inflammatory Compounds

N-acylethanolamine-hydrolyzing acid amidase (NAAA) is a lysosomal enzyme involved in biological deactivation of N-palmitoylethanolamide (PEA), which exerts anti-inflammatory and analgesic effects through the activation of nuclear receptor peroxisome proliferator-activated receptor-alpha (PPAR-α). To...

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Detalles Bibliográficos
Autores principales: Li, Yuhang, Yang, Longhe, Chen, Ling, Zhu, Chenggang, Huang, Rui, Zheng, Xiao, Qiu, Yan, Fu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423427/
https://www.ncbi.nlm.nih.gov/pubmed/22916199
http://dx.doi.org/10.1371/journal.pone.0043023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423427/
https://www.ncbi.nlm.nih.gov/pubmed/22916199
http://dx.doi.org/10.1371/journal.pone.0043023

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