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Neuron-Specific Deletion of Peroxisome Proliferator-Activated Receptor Delta (PPARδ) in Mice Leads to Increased Susceptibility to Diet-Induced Obesity
Central nervous system (CNS) lipid accumulation, inflammation and resistance to adipo-regulatory hormones, such as insulin and leptin, are implicated in the pathogenesis of diet-induced obesity (DIO). Peroxisome proliferator-activated receptors (PPAR α, δ, γ) are nuclear transcription factors that a...
Autores principales: | Kocalis, Heidi E., Turney, Maxine K., Printz, Richard L., Laryea, Gloria N., Muglia, Louis J., Davies, Sean S., Stanwood, Gregg D., McGuinness, Owen P., Niswender, Kevin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423438/ https://www.ncbi.nlm.nih.gov/pubmed/22916190 http://dx.doi.org/10.1371/journal.pone.0042981 |
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