A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test

Allopurinol is one of the causative drugs that induce fixed drug eruption (FDE). The lymphocyte transformation test (LTT) is a safe and reliable diagnostic procedure for drug allergy, but is reported to be rarely positive in patients with FDE. In the current case, we performed an LTT and successfull...

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Autores principales: Kim, Min-Hye, Shim, Eun-Jin, Jung, Jae-Woo, Sohn, Seong-Wook, Kang, Hye-Ryun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423606/
https://www.ncbi.nlm.nih.gov/pubmed/22950038
http://dx.doi.org/10.4168/aair.2012.4.5.309
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author Kim, Min-Hye
Shim, Eun-Jin
Jung, Jae-Woo
Sohn, Seong-Wook
Kang, Hye-Ryun
author_facet Kim, Min-Hye
Shim, Eun-Jin
Jung, Jae-Woo
Sohn, Seong-Wook
Kang, Hye-Ryun
author_sort Kim, Min-Hye
collection PubMed
description Allopurinol is one of the causative drugs that induce fixed drug eruption (FDE). The lymphocyte transformation test (LTT) is a safe and reliable diagnostic procedure for drug allergy, but is reported to be rarely positive in patients with FDE. In the current case, we performed an LTT and successfully confirmed allopurinol as the offending drug. This case report suggests that an LTT should be an optional diagnostic tool for FDE or delayed reaction due to allopurinol.
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spelling pubmed-34236062012-09-05 A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test Kim, Min-Hye Shim, Eun-Jin Jung, Jae-Woo Sohn, Seong-Wook Kang, Hye-Ryun Allergy Asthma Immunol Res Case Report Allopurinol is one of the causative drugs that induce fixed drug eruption (FDE). The lymphocyte transformation test (LTT) is a safe and reliable diagnostic procedure for drug allergy, but is reported to be rarely positive in patients with FDE. In the current case, we performed an LTT and successfully confirmed allopurinol as the offending drug. This case report suggests that an LTT should be an optional diagnostic tool for FDE or delayed reaction due to allopurinol. The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2012-09 2012-03-29 /pmc/articles/PMC3423606/ /pubmed/22950038 http://dx.doi.org/10.4168/aair.2012.4.5.309 Text en Copyright © 2012 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Min-Hye
Shim, Eun-Jin
Jung, Jae-Woo
Sohn, Seong-Wook
Kang, Hye-Ryun
A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test
title A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test
title_full A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test
title_fullStr A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test
title_full_unstemmed A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test
title_short A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test
title_sort case of allopurinol-induced fixed drug eruption confirmed with a lymphocyte transformation test
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423606/
https://www.ncbi.nlm.nih.gov/pubmed/22950038
http://dx.doi.org/10.4168/aair.2012.4.5.309
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