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Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms
Based on Darwin's concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions, and duplication were streaming the genomes of living organisms. In the current genomic era, increasing data indicated that both vertical and lateral gene inheritance interac...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423634/ https://www.ncbi.nlm.nih.gov/pubmed/22919697 http://dx.doi.org/10.3389/fcimb.2012.00110 |
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author | Bertelli, Claire Greub, Gilbert |
author_facet | Bertelli, Claire Greub, Gilbert |
author_sort | Bertelli, Claire |
collection | PubMed |
description | Based on Darwin's concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions, and duplication were streaming the genomes of living organisms. In the current genomic era, increasing data indicated that both vertical and lateral gene inheritance interact in space and time to trigger genome evolution, particularly among microorganisms sharing a given ecological niche. As a paradigm to their diversity and their survival in a variety of cell types, intracellular microorganisms, and notably intracellular bacteria, were considered as less prone to lateral genetic exchanges. Such specialized microorganisms generally have a smaller gene repertoire because they do rely on their host's factors for some basic regulatory and metabolic functions. Here we review events of lateral gene transfer (LGT) that illustrate the genetic exchanges among intra-amoebal microorganisms or between the microorganism and its amoebal host. We tentatively investigate the functions of laterally transferred genes in the light of the interaction with their host as they should confer a selective advantage and success to the amoeba-resisting microorganisms (ARMs). |
format | Online Article Text |
id | pubmed-3423634 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-34236342012-08-23 Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms Bertelli, Claire Greub, Gilbert Front Cell Infect Microbiol Microbiology Based on Darwin's concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions, and duplication were streaming the genomes of living organisms. In the current genomic era, increasing data indicated that both vertical and lateral gene inheritance interact in space and time to trigger genome evolution, particularly among microorganisms sharing a given ecological niche. As a paradigm to their diversity and their survival in a variety of cell types, intracellular microorganisms, and notably intracellular bacteria, were considered as less prone to lateral genetic exchanges. Such specialized microorganisms generally have a smaller gene repertoire because they do rely on their host's factors for some basic regulatory and metabolic functions. Here we review events of lateral gene transfer (LGT) that illustrate the genetic exchanges among intra-amoebal microorganisms or between the microorganism and its amoebal host. We tentatively investigate the functions of laterally transferred genes in the light of the interaction with their host as they should confer a selective advantage and success to the amoeba-resisting microorganisms (ARMs). Frontiers Media S.A. 2012-08-21 /pmc/articles/PMC3423634/ /pubmed/22919697 http://dx.doi.org/10.3389/fcimb.2012.00110 Text en Copyright © 2012 Bertelli and Greub. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. |
spellingShingle | Microbiology Bertelli, Claire Greub, Gilbert Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
title | Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
title_full | Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
title_fullStr | Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
title_full_unstemmed | Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
title_short | Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
title_sort | lateral gene exchanges shape the genomes of amoeba-resisting microorganisms |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423634/ https://www.ncbi.nlm.nih.gov/pubmed/22919697 http://dx.doi.org/10.3389/fcimb.2012.00110 |
work_keys_str_mv | AT bertelliclaire lateralgeneexchangesshapethegenomesofamoebaresistingmicroorganisms AT greubgilbert lateralgeneexchangesshapethegenomesofamoebaresistingmicroorganisms |