Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells

Recent reports on direct reprogramming of cancer cells (iPCs) which results in reduced tumorigenic potential has attributed the importance of epigenetics in tumorigenesis, but lacked genome-wide analysis. Here we describe successful generation of iPCs from non-small cell lung cancer (NSCLC) cell lin...

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Detalles Bibliográficos
Autores principales: Mahalingam, Dashayini, Kong, Chiou Mee, Lai, Jason, Tay, Ling Lee, Yang, Henry, Wang, Xueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423637/
https://www.ncbi.nlm.nih.gov/pubmed/22912920
http://dx.doi.org/10.1038/srep00592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423637/
https://www.ncbi.nlm.nih.gov/pubmed/22912920
http://dx.doi.org/10.1038/srep00592

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