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Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells
Recent reports on direct reprogramming of cancer cells (iPCs) which results in reduced tumorigenic potential has attributed the importance of epigenetics in tumorigenesis, but lacked genome-wide analysis. Here we describe successful generation of iPCs from non-small cell lung cancer (NSCLC) cell lin...
Autores principales: | Mahalingam, Dashayini, Kong, Chiou Mee, Lai, Jason, Tay, Ling Lee, Yang, Henry, Wang, Xueying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423637/ https://www.ncbi.nlm.nih.gov/pubmed/22912920 http://dx.doi.org/10.1038/srep00592 |
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