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Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)

BACKGROUND: The GammaPlan(™) treatment planning system (TPS) does not fully account for shutter dose when multiple shots are required to deliver a patient’s treatment. The unaccounted exposures to the target site and its periphery are measured in this study. The collected data are compared to a simi...

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Autores principales: Tran, Tuan-Anh, Wu, Vincent, Malhotra, Harish, Steinman, James P., Prasad, Dheerendra, Podgorsak, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita, Warsaw 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423725/
https://www.ncbi.nlm.nih.gov/pubmed/22933947
http://dx.doi.org/10.2478/v10019-011-0012-9
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author Tran, Tuan-Anh
Wu, Vincent
Malhotra, Harish
Steinman, James P.
Prasad, Dheerendra
Podgorsak, Matthew B.
author_facet Tran, Tuan-Anh
Wu, Vincent
Malhotra, Harish
Steinman, James P.
Prasad, Dheerendra
Podgorsak, Matthew B.
author_sort Tran, Tuan-Anh
collection PubMed
description BACKGROUND: The GammaPlan(™) treatment planning system (TPS) does not fully account for shutter dose when multiple shots are required to deliver a patient’s treatment. The unaccounted exposures to the target site and its periphery are measured in this study. The collected data are compared to a similar effect from the Gamma Knife(®) model 4C. MATERIALS AND METHODS. A stereotactic head frame was attached to a Leksell(®) 16 cm diameter spherical phantom; using a fiducial-box, CT images of the phantom were acquired and registered in the TPS. Measurements give the relationship of measured dose to the number of repositions with the patient positioning system (PPS) and to the collimator size. An absorbed dose of 10 Gy to the 50% isodose line was prescribed to the target site and all measurements were acquired with an ionization chamber. RESULTS: Measured dose increases with frequency of repositioning and with collimator size. As the radiation sectors transition between the beam on and beam off states, the target receives more shutter dose than the periphery. Shutter doses of 3.53±0.04 and 1.59±0.04 cGy/reposition to the target site are observed for the 16 and 8 mm collimators, respectively. The target periphery receives additional dose that varies depending on its position relative to the target. CONCLUSIONS: The radiation sector motions for the Gamma Knife(®) Perfexion(™) result in an additional dose due to the shutter effect. The magnitude of this exposure is comparable to that measured for the model 4C.
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spelling pubmed-34237252012-08-29 Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™) Tran, Tuan-Anh Wu, Vincent Malhotra, Harish Steinman, James P. Prasad, Dheerendra Podgorsak, Matthew B. Radiol Oncol Research Article BACKGROUND: The GammaPlan(™) treatment planning system (TPS) does not fully account for shutter dose when multiple shots are required to deliver a patient’s treatment. The unaccounted exposures to the target site and its periphery are measured in this study. The collected data are compared to a similar effect from the Gamma Knife(®) model 4C. MATERIALS AND METHODS. A stereotactic head frame was attached to a Leksell(®) 16 cm diameter spherical phantom; using a fiducial-box, CT images of the phantom were acquired and registered in the TPS. Measurements give the relationship of measured dose to the number of repositions with the patient positioning system (PPS) and to the collimator size. An absorbed dose of 10 Gy to the 50% isodose line was prescribed to the target site and all measurements were acquired with an ionization chamber. RESULTS: Measured dose increases with frequency of repositioning and with collimator size. As the radiation sectors transition between the beam on and beam off states, the target receives more shutter dose than the periphery. Shutter doses of 3.53±0.04 and 1.59±0.04 cGy/reposition to the target site are observed for the 16 and 8 mm collimators, respectively. The target periphery receives additional dose that varies depending on its position relative to the target. CONCLUSIONS: The radiation sector motions for the Gamma Knife(®) Perfexion(™) result in an additional dose due to the shutter effect. The magnitude of this exposure is comparable to that measured for the model 4C. Versita, Warsaw 2011-04-23 /pmc/articles/PMC3423725/ /pubmed/22933947 http://dx.doi.org/10.2478/v10019-011-0012-9 Text en Copyright © by Association of Radiology & Oncology http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Research Article
Tran, Tuan-Anh
Wu, Vincent
Malhotra, Harish
Steinman, James P.
Prasad, Dheerendra
Podgorsak, Matthew B.
Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)
title Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)
title_full Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)
title_fullStr Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)
title_full_unstemmed Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)
title_short Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife(®) Perfexion(™)
title_sort target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the gamma knife(®) perfexion(™)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423725/
https://www.ncbi.nlm.nih.gov/pubmed/22933947
http://dx.doi.org/10.2478/v10019-011-0012-9
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