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Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)

BACKGROUND: The early determination of premalignant lesions of pancreas can prevent unnecessary excessive surgical procedures and can reduce morbidity and mortality. Pancreatic intraepithelial neoplasia-3 (PanIN-3) is a preinvasive form of adenocarcinoma (carcinoma in situ). PanINs have not taken pl...

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Autores principales: Algin, Oktay, Ozmen, Evrim, Ersoy, Pamir Eren, Karaoglanoglu, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita, Warsaw 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423746/
https://www.ncbi.nlm.nih.gov/pubmed/22933970
http://dx.doi.org/10.2478/v10019-011-0035-2
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author Algin, Oktay
Ozmen, Evrim
Ersoy, Pamir Eren
Karaoglanoglu, Mustafa
author_facet Algin, Oktay
Ozmen, Evrim
Ersoy, Pamir Eren
Karaoglanoglu, Mustafa
author_sort Algin, Oktay
collection PubMed
description BACKGROUND: The early determination of premalignant lesions of pancreas can prevent unnecessary excessive surgical procedures and can reduce morbidity and mortality. Pancreatic intraepithelial neoplasia-3 (PanIN-3) is a preinvasive form of adenocarcinoma (carcinoma in situ). PanINs have not taken place in the literature of radiology yet, it should be considered in differential diagnosis of pancreatic cystic lesions. CASE REPORT: A patient with preliminary diagnosis of chronic cholecystitis who had choledocolithiasis and periampullary pancreatic cyst detected by noncontrast-enhanced (NCE) and contrast-enhanced (CE) magnetic resonance cholangiography (MRCP) is presented. Pathological examination results of gallbladder and pancreatic cyst were reported as gallbladder adenocarcinoma and PanIN-3, respectively. CONCLUSIONS: Pancreatic cystic lesions with thin septa which enhances slightly with the administration of contrast material may represent PanIN-3. In patients with cystic pancreatic lesion localized at periampullary region, using CE-MRCP together with NCE-MRCP could be useful in the evaluation of pancreatic cystic masses as well as other abdominal pathologies.
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spelling pubmed-34237462012-08-29 Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP) Algin, Oktay Ozmen, Evrim Ersoy, Pamir Eren Karaoglanoglu, Mustafa Radiol Oncol Case Report BACKGROUND: The early determination of premalignant lesions of pancreas can prevent unnecessary excessive surgical procedures and can reduce morbidity and mortality. Pancreatic intraepithelial neoplasia-3 (PanIN-3) is a preinvasive form of adenocarcinoma (carcinoma in situ). PanINs have not taken place in the literature of radiology yet, it should be considered in differential diagnosis of pancreatic cystic lesions. CASE REPORT: A patient with preliminary diagnosis of chronic cholecystitis who had choledocolithiasis and periampullary pancreatic cyst detected by noncontrast-enhanced (NCE) and contrast-enhanced (CE) magnetic resonance cholangiography (MRCP) is presented. Pathological examination results of gallbladder and pancreatic cyst were reported as gallbladder adenocarcinoma and PanIN-3, respectively. CONCLUSIONS: Pancreatic cystic lesions with thin septa which enhances slightly with the administration of contrast material may represent PanIN-3. In patients with cystic pancreatic lesion localized at periampullary region, using CE-MRCP together with NCE-MRCP could be useful in the evaluation of pancreatic cystic masses as well as other abdominal pathologies. Versita, Warsaw 2011-11-16 /pmc/articles/PMC3423746/ /pubmed/22933970 http://dx.doi.org/10.2478/v10019-011-0035-2 Text en Copyright © by Association of Radiology & Oncology http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Case Report
Algin, Oktay
Ozmen, Evrim
Ersoy, Pamir Eren
Karaoglanoglu, Mustafa
Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
title Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
title_full Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
title_fullStr Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
title_full_unstemmed Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
title_short Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
title_sort periampullary localized pancreatic intraepithelial neoplasia-3 (panin-3): evaluation with contrast-enhanced mr cholangiography (mrcp)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423746/
https://www.ncbi.nlm.nih.gov/pubmed/22933970
http://dx.doi.org/10.2478/v10019-011-0035-2
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