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Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil

PURPOSE: This prospective study evaluated the effects of continuous sedation using midazolam, with or without remifentanil, on postoperative nausea and vomiting (PONV) in patients undergoing myringoplasty. MATERIALS AND METHODS: Sixty patients undergoing myringoplasty were sedated with midazolam in...

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Autores principales: Jang, Ji Su, Lee, Jun Ho, Lee, Jae Jun, Park, Won Jae, Hwang, Sung Mi, Lee, Soo Kyung, Lim, So Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423846/
https://www.ncbi.nlm.nih.gov/pubmed/22869486
http://dx.doi.org/10.3349/ymj.2012.53.5.1010
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author Jang, Ji Su
Lee, Jun Ho
Lee, Jae Jun
Park, Won Jae
Hwang, Sung Mi
Lee, Soo Kyung
Lim, So Young
author_facet Jang, Ji Su
Lee, Jun Ho
Lee, Jae Jun
Park, Won Jae
Hwang, Sung Mi
Lee, Soo Kyung
Lim, So Young
author_sort Jang, Ji Su
collection PubMed
description PURPOSE: This prospective study evaluated the effects of continuous sedation using midazolam, with or without remifentanil, on postoperative nausea and vomiting (PONV) in patients undergoing myringoplasty. MATERIALS AND METHODS: Sixty patients undergoing myringoplasty were sedated with midazolam in the presence of remifentanil (group MR), or after saline injection instead of remifentanil (group M). RESULTS: Three patients (10%) in group M complained of nausea; two vomited. Four patients (13%) in group MR complained of nausea and vomited within 24 h after surgery. Rescue drugs were given to the six patients who vomited. No significant difference was detected between the two groups regarding the incidence or severity of nausea, incidence of vomiting, or need for rescue drugs. CONCLUSION: Midazolam-based continuous sedation can reduce PONV after myringoplasty. Compared with midazolam alone, midazolam with remifentanil produced no difference in the incidence or severity of nausea, incidence of vomiting, or need for rescue drugs.
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spelling pubmed-34238462012-09-05 Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil Jang, Ji Su Lee, Jun Ho Lee, Jae Jun Park, Won Jae Hwang, Sung Mi Lee, Soo Kyung Lim, So Young Yonsei Med J Original Article PURPOSE: This prospective study evaluated the effects of continuous sedation using midazolam, with or without remifentanil, on postoperative nausea and vomiting (PONV) in patients undergoing myringoplasty. MATERIALS AND METHODS: Sixty patients undergoing myringoplasty were sedated with midazolam in the presence of remifentanil (group MR), or after saline injection instead of remifentanil (group M). RESULTS: Three patients (10%) in group M complained of nausea; two vomited. Four patients (13%) in group MR complained of nausea and vomited within 24 h after surgery. Rescue drugs were given to the six patients who vomited. No significant difference was detected between the two groups regarding the incidence or severity of nausea, incidence of vomiting, or need for rescue drugs. CONCLUSION: Midazolam-based continuous sedation can reduce PONV after myringoplasty. Compared with midazolam alone, midazolam with remifentanil produced no difference in the incidence or severity of nausea, incidence of vomiting, or need for rescue drugs. Yonsei University College of Medicine 2012-09-01 2012-07-25 /pmc/articles/PMC3423846/ /pubmed/22869486 http://dx.doi.org/10.3349/ymj.2012.53.5.1010 Text en © Copyright: Yonsei University College of Medicine 2012 http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jang, Ji Su
Lee, Jun Ho
Lee, Jae Jun
Park, Won Jae
Hwang, Sung Mi
Lee, Soo Kyung
Lim, So Young
Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil
title Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil
title_full Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil
title_fullStr Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil
title_full_unstemmed Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil
title_short Postoperative Nausea and Vomiting after Myringoplasty under Continuous Sedation Using Midazolam with or without Remifentanil
title_sort postoperative nausea and vomiting after myringoplasty under continuous sedation using midazolam with or without remifentanil
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423846/
https://www.ncbi.nlm.nih.gov/pubmed/22869486
http://dx.doi.org/10.3349/ymj.2012.53.5.1010
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