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Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1
BACKGROUND: Prolonged exposure to hyperoxia in neonates can cause hyperoxic acute lung injury (HALI), which is characterized by increased pulmonary permeability and diffuse infiltration of various inflammatory cells. Disruption of the epithelial barrier may lead to altered pulmonary permeability and...
Autores principales: | You, Kai, Xu, Xuewen, Fu, Jianhua, Xu, Shuyan, Yue, Xiaohong, Yu, Zhiling, Xue, Xindong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424121/ https://www.ncbi.nlm.nih.gov/pubmed/22559818 http://dx.doi.org/10.1186/1465-9921-13-36 |
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