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Runx2 Haploinsufficiency Ameliorates the Development of Ossification of the Posterior Longitudinal Ligament
Ossification of the Posterior Longitudinal Ligament (OPLL) is a disease that is characterized by the ectopic calcification of the ligament; however, the pathogenesis of OPLL remains to be investigated. We attempted to identify the in vivo role of Runx2, a master regulator of osteoblast differentiati...
Autores principales: | Iwasaki, Makiko, Piao, Jinying, Kimura, Ayako, Sato, Shingo, Inose, Hiroyuki, Ochi, Hiroki, Asou, Yoshinori, Shinomiya, Kenichi, Okawa, Atsushi, Takeda, Shu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424156/ https://www.ncbi.nlm.nih.gov/pubmed/22927960 http://dx.doi.org/10.1371/journal.pone.0043372 |
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