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Gelsolin Induces Colorectal Tumor Cell Invasion via Modulation of the Urokinase-Type Plasminogen Activator Cascade
Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and therapy-resistance. In vitro, gelsolin has anti-apop...
Autores principales: | Zhuo, Jingli, Tan, Ee Hong, Yan, Benedict, Tochhawng, Lalchhandami, Jayapal, Manikandan, Koh, Shiuan, Tay, Hwee Kee, Maciver, Sutherland K., Hooi, Shing Chuan, Salto-Tellez, Manuel, Kumar, Alan Prem, Goh, Yaw Chong, Lim, Yaw Chyn, Yap, Celestial T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424201/ https://www.ncbi.nlm.nih.gov/pubmed/22927998 http://dx.doi.org/10.1371/journal.pone.0043594 |
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