Comparative Proteomics Reveals a Significant Bias Toward Alternative Protein Isoforms with Conserved Structure and Function

Advances in high-throughput mass spectrometry are making proteomics an increasingly important tool in genome annotation projects. Peptides detected in mass spectrometry experiments can be used to validate gene models and verify the translation of putative coding sequences (CDSs). Here, we have ident...

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Detalles Bibliográficos
Autores principales: Ezkurdia, Iakes, del Pozo, Angela, Frankish, Adam, Rodriguez, Jose Manuel, Harrow, Jennifer, Ashman, Keith, Valencia, Alfonso, Tress, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424414/
https://www.ncbi.nlm.nih.gov/pubmed/22446687
http://dx.doi.org/10.1093/molbev/mss100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424414/
https://www.ncbi.nlm.nih.gov/pubmed/22446687
http://dx.doi.org/10.1093/molbev/mss100

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