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Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model

Individuals with metabolic syndrome are at high risk of developing chronic kidney disease (CKD) through unclear pathogenic mechanisms. Obesity and diabetes are known to induce glucolipotoxic effects in metabolically relevant organs. However, the pathogenic role of glucolipotoxicity in the aetiology...

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Detalles Bibliográficos
Autores principales: Martínez-García, Cristina, Izquierdo, Adriana, Velagapudi, Vidya, Vivas, Yurena, Velasco, Ismael, Campbell, Mark, Burling, Keith, Cava, Fernando, Ros, Manuel, Orešič, Matej, Vidal-Puig, Antonio, Medina-Gomez, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424461/
https://www.ncbi.nlm.nih.gov/pubmed/22773754
http://dx.doi.org/10.1242/dmm.009266