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High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

The mediobasal hypothalamic arcuate nucleus (ARC), with its relatively ‘leaky’ blood-brain barrier that allows more circulating molecules to enter the brain, has emerged as a key sensor of blood-borne signals. In both the ARC and white adipose tissue (WAT), consumption of a high-fat diet (HFD) rapid...

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Detalles Bibliográficos
Autores principales: Yi, Chun-Xia, Tschöp, Matthias H., Woods, Stephen C., Hofmann, Susanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424466/
https://www.ncbi.nlm.nih.gov/pubmed/22381575
http://dx.doi.org/10.1242/dmm.009464

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