The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine

DNA cytosine methylation is a widespread epigenetic mark. Biological effects of DNA methylation are mediated by the proteins that preferentially bind to 5-methylcytosine (5mC) in different sequence contexts. Until now two different structural mechanisms have been established for 5mC recognition in e...

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Detalles Bibliográficos
Autores principales: Sukackaite, Rasa, Grazulis, Saulius, Tamulaitis, Gintautas, Siksnys, Virginijus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424535/
https://www.ncbi.nlm.nih.gov/pubmed/22570415
http://dx.doi.org/10.1093/nar/gks332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424535/
https://www.ncbi.nlm.nih.gov/pubmed/22570415
http://dx.doi.org/10.1093/nar/gks332

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