The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3′-UTR truncation in round spermatids

Members of the BET (bromodomain and extra terminal motif) family of proteins have been shown to be chromatin-interacting regulators of transcription. We previously generated a mutation in the testis-specific mammalian BET gene Brdt (bromodomain, testis-specific) that yields protein lacking the first...

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Detalles Bibliográficos
Autores principales: Berkovits, Binyamin D., Wang, Li, Guarnieri, Paolo, Wolgemuth, Debra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424537/
https://www.ncbi.nlm.nih.gov/pubmed/22570411
http://dx.doi.org/10.1093/nar/gks342

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