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The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ

Although most DNA polymerases discriminate against ribonucleotide triphosphaets (rNTPs) during DNA synthesis, recent studies have shown that large numbers of ribonucleotides are incorporated into the eukaryotic nuclear genome. Here, we investigate how a DNA polymerase can stably incorporate an rNTP....

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Detalles Bibliográficos
Autores principales:	Gosavi, Rajendrakumar A., Moon, Andrea F., Kunkel, Thomas A., Pedersen, Lars C., Bebenek, Katarzyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424563/ https://www.ncbi.nlm.nih.gov/pubmed/22584622 http://dx.doi.org/10.1093/nar/gks413

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