Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H(37)Rv and H(37)Ra reveal novel and interesting differences with implications in virulence

Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease taking one human life every 15 s globally. The two well-characterized strains H(37)Rv and H(37)Ra, derived from the same parental strain M. tuberculosis H(37), show dramatically different pathogenic phenotypes....

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Detalles Bibliográficos
Autores principales: Kohli, Sakshi, Singh, Yadvir, Sharma, Khushbu, Mittal, Aditya, Ehtesham, Nasreen Z., Hasnain, Seyed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424577/
https://www.ncbi.nlm.nih.gov/pubmed/22618876
http://dx.doi.org/10.1093/nar/gks465

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