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Prolonged sulforaphane treatment does not enhance tumorigenesis in oncogenic K-ras and xenograft mouse models of lung cancer

BACKGROUND: Sulforaphane (SFN), an activator of nuclear factor erythroid-2 related factor 2 (Nrf2), is a promising chemopreventive agent which is undergoing clinical trial for several diseases. Studies have indicated that there is gain of Nrf2 function in lung cancer and other solid tumors because o...

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Detalles Bibliográficos
Autores principales:	Kombairaju, Ponvijay, Ma, Jinfang, Thimmulappa, Rajesh K, Yan, Shengbin G, Gabrielson, Edward, Singh, Anju, Biswal, Shyam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424666/ https://www.ncbi.nlm.nih.gov/pubmed/22919281 http://dx.doi.org/10.4103/1477-3163.98459

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