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Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report
We report a case of penile metastases from recurrent prostatic adenocarcinoma that was the first sign of a widespread metastatic disease in the absence of any increase in prostate-specific antigen (PSA) level. In April 2011, an 80-year-old man presented to our Radiotherapy Unit with multiple palpabl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424701/ https://www.ncbi.nlm.nih.gov/pubmed/22919558 http://dx.doi.org/10.4103/2156-7514.99178 |
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author | Pierro, Antonio Cilla, Savino Digesù, Cinzia Morganti, Alessio G. |
author_facet | Pierro, Antonio Cilla, Savino Digesù, Cinzia Morganti, Alessio G. |
author_sort | Pierro, Antonio |
collection | PubMed |
description | We report a case of penile metastases from recurrent prostatic adenocarcinoma that was the first sign of a widespread metastatic disease in the absence of any increase in prostate-specific antigen (PSA) level. In April 2011, an 80-year-old man presented to our Radiotherapy Unit with multiple palpable hard nodules in the penis, dysuria, and moderate perineal pain, 7 years after he had received radiotherapy for prostate cancer. Nodules in the penis had appeared in February 2011. The ultrasound and magnetic resonance (MR) imaging suggested the diagnosis of multiple penile metastases. A total body computed tomography scan revealed a systemic spread of the disease, with multiple metastases in the liver, bones, and lungs. PSA level was 0.126 ng/ml. A fine needle aspiration biopsy of the liver lesion was undertaken, and the histopathologic examination revealed the prostatic origin of the metastases, so androgen deprivation therapy was started. The diagnosis of metastases should be considered in a patient with prior history of prostate malignancies presenting with solid nodules in the penis, even if the PSA level is low. |
format | Online Article Text |
id | pubmed-3424701 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34247012012-08-23 Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report Pierro, Antonio Cilla, Savino Digesù, Cinzia Morganti, Alessio G. J Clin Imaging Sci Case Report We report a case of penile metastases from recurrent prostatic adenocarcinoma that was the first sign of a widespread metastatic disease in the absence of any increase in prostate-specific antigen (PSA) level. In April 2011, an 80-year-old man presented to our Radiotherapy Unit with multiple palpable hard nodules in the penis, dysuria, and moderate perineal pain, 7 years after he had received radiotherapy for prostate cancer. Nodules in the penis had appeared in February 2011. The ultrasound and magnetic resonance (MR) imaging suggested the diagnosis of multiple penile metastases. A total body computed tomography scan revealed a systemic spread of the disease, with multiple metastases in the liver, bones, and lungs. PSA level was 0.126 ng/ml. A fine needle aspiration biopsy of the liver lesion was undertaken, and the histopathologic examination revealed the prostatic origin of the metastases, so androgen deprivation therapy was started. The diagnosis of metastases should be considered in a patient with prior history of prostate malignancies presenting with solid nodules in the penis, even if the PSA level is low. Medknow Publications & Media Pvt Ltd 2012-07-28 /pmc/articles/PMC3424701/ /pubmed/22919558 http://dx.doi.org/10.4103/2156-7514.99178 Text en Copyright: © 2012 Pierro, et al. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Case Report Pierro, Antonio Cilla, Savino Digesù, Cinzia Morganti, Alessio G. Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report |
title | Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report |
title_full | Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report |
title_fullStr | Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report |
title_full_unstemmed | Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report |
title_short | Penile Metastases of Recurrent Prostatic Adenocarcinoma without PSA Level Increase: A Case Report |
title_sort | penile metastases of recurrent prostatic adenocarcinoma without psa level increase: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424701/ https://www.ncbi.nlm.nih.gov/pubmed/22919558 http://dx.doi.org/10.4103/2156-7514.99178 |
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