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Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements

Due to their ability to drive DNA rearrangements and to serve as a source of new coding and regulatory sequences, transposable elements (TEs) are considered as powerful evolutionary agents within genomes. In this paper, we review the mechanism of molecular domestication, which corresponds to the for...

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Autores principales: Chalopin, Domitille, Galiana, Delphine, Volff, Jean-Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424704/
https://www.ncbi.nlm.nih.gov/pubmed/22928150
http://dx.doi.org/10.1155/2012/724519
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author Chalopin, Domitille
Galiana, Delphine
Volff, Jean-Nicolas
author_facet Chalopin, Domitille
Galiana, Delphine
Volff, Jean-Nicolas
author_sort Chalopin, Domitille
collection PubMed
description Due to their ability to drive DNA rearrangements and to serve as a source of new coding and regulatory sequences, transposable elements (TEs) are considered as powerful evolutionary agents within genomes. In this paper, we review the mechanism of molecular domestication, which corresponds to the formation of new genes derived from TE sequences. Many genes derived from retroelements and DNA transposons have been identified in mammals and other vertebrates, some of them fulfilling essential functions for the development and survival of their host organisms. We will particularly focus on the evolution and expression of Gypsy integrase (GIN) genes, which have been formed from ancient event(s) of molecular domestication and have evolved differentially in some vertebrate sublineages. What we describe here is probably only the tip of the evolutionary iceberg, and future genome analyses will certainly uncover new TE-derived genes and biological functions driving genetic innovation in vertebrates and other organisms.
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spelling pubmed-34247042012-08-27 Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements Chalopin, Domitille Galiana, Delphine Volff, Jean-Nicolas Int J Evol Biol Research Article Due to their ability to drive DNA rearrangements and to serve as a source of new coding and regulatory sequences, transposable elements (TEs) are considered as powerful evolutionary agents within genomes. In this paper, we review the mechanism of molecular domestication, which corresponds to the formation of new genes derived from TE sequences. Many genes derived from retroelements and DNA transposons have been identified in mammals and other vertebrates, some of them fulfilling essential functions for the development and survival of their host organisms. We will particularly focus on the evolution and expression of Gypsy integrase (GIN) genes, which have been formed from ancient event(s) of molecular domestication and have evolved differentially in some vertebrate sublineages. What we describe here is probably only the tip of the evolutionary iceberg, and future genome analyses will certainly uncover new TE-derived genes and biological functions driving genetic innovation in vertebrates and other organisms. Hindawi Publishing Corporation 2012 2012-08-13 /pmc/articles/PMC3424704/ /pubmed/22928150 http://dx.doi.org/10.1155/2012/724519 Text en Copyright © 2012 Domitille Chalopin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chalopin, Domitille
Galiana, Delphine
Volff, Jean-Nicolas
Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements
title Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements
title_full Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements
title_fullStr Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements
title_full_unstemmed Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements
title_short Genetic Innovation in Vertebrates: Gypsy Integrase Genes and Other Genes Derived from Transposable Elements
title_sort genetic innovation in vertebrates: gypsy integrase genes and other genes derived from transposable elements
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424704/
https://www.ncbi.nlm.nih.gov/pubmed/22928150
http://dx.doi.org/10.1155/2012/724519
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