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Dynamic PET and Optical Imaging and Compartment Modeling using a Dual-labeled Cyclic RGD Peptide Probe

Purpose: The aim of this study is to determine if dynamic optical imaging could provide comparable kinetic parameters to that of dynamic PET imaging by a near-infrared dye/(64)Cu dual-labeled cyclic RGD peptide. Methods: The integrin α(v)β(3) binding RGD peptide was conjugated with a macrocyclic che...

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Detalles Bibliográficos
Autores principales: Zhu, Lei, Guo, Ning, Li, Quanzheng, Ma, Ying, Jacboson, Orit, Lee, Seulki, Choi, Hak Soo, Mansfield, James R., Niu, Gang, Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425122/
https://www.ncbi.nlm.nih.gov/pubmed/22916074
http://dx.doi.org/10.7150/thno.4762