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A functional tonB gene is required for both virulence and competitive fitness in a chinchilla model of Haemophilus influenzae otitis media

BACKGROUND: Haemophilus influenzae requires heme for aerobic growth and possesses multiple mechanisms to obtain this essential nutrient. METHODS: An insertional mutation in tonB was constructed and the impact of the mutation on virulence and fitness in a chinchilla model of otitis media was determin...

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Detalles Bibliográficos
Autores principales:	Morton, Daniel J, Hempel, Randy J, Seale, Thomas W, Whitby, Paul W, Stull, Terrence L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425130/ https://www.ncbi.nlm.nih.gov/pubmed/22731867 http://dx.doi.org/10.1186/1756-0500-5-327

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