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Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells
BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) induces neuronal dysfunction through host cellular factors and viral proteins including viral protein R (Vpr) released from infected macrophages/microglia. Vpr is important for infection of terminally differentiated cells such as macrophages. T...
Autores principales: | Guha, Debjani, Nagilla, Pruthvi, Redinger, Carrie, Srinivasan, Alagarsamy, Schatten, Gerald P, Ayyavoo, Velpandi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425332/ https://www.ncbi.nlm.nih.gov/pubmed/22727020 http://dx.doi.org/10.1186/1742-2094-9-138 |
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