Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10-Producing Regulatory B Cells and High BAFF Levels

BACKGROUND: Sarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved. Plasmatic hypergammaglobulinemia and B cell accumulation in granulomatous lesions suggest the possible role of humoral immune responses...

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Detalles Bibliográficos
Autores principales: Saussine, Anne, Tazi, Abdellatif, Feuillet, Séverine, Rybojad, Michel, Juillard, Caroline, Bergeron, Anne, Dessirier, Valérie, Bouhidel, Fatiha, Janin, Anne, Bensussan, Armand, Bagot, Martine, Bouaziz, Jean-David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425471/
https://www.ncbi.nlm.nih.gov/pubmed/22927996
http://dx.doi.org/10.1371/journal.pone.0043588

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