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Glycoform and Net Charge Heterogeneity in gp120 Immunogens Used in HIV Vaccine Trials
BACKGROUND: The RV144 clinical trial showed for the first time that vaccination could provide modest but significant protection from HIV-1 infection. To understand the protective response, and to improve upon the vaccine's efficacy, it is important to define the structure of the immunogens used...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425498/ https://www.ncbi.nlm.nih.gov/pubmed/22928048 http://dx.doi.org/10.1371/journal.pone.0043903 |