Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Transcription Factor NF-κB in R-HepG2 Cell Line

Multidrug resistance(MDR)is one of the major reasons for failure in cancer chemotherapy and its suppression may increase the efficacy of therapy. The human multidrug resistance 1 (MDR1) gene encodes the plasma membrane P-glycoprotein (P-gp) that pumps various anti-cancer agents out of the cancer cel...

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Detalles Bibliográficos
Autores principales: Sun, Jianguo, Yeung, Chilam Au, Co, Ngai Na, Tsang, Tsun Yee, Yau, Esmond, Luo, Kewang, Wu, Ping, Wa, Judy Chan Yuet, Fung, Kwok-Pui, Kwok, Tim-Tak, Liu, Feiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425549/
https://www.ncbi.nlm.nih.gov/pubmed/22927901
http://dx.doi.org/10.1371/journal.pone.0040720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425549/
https://www.ncbi.nlm.nih.gov/pubmed/22927901
http://dx.doi.org/10.1371/journal.pone.0040720

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